Transgender men who lose 10 to 15 pounds (4. 8 to 6. 8 kg) after starting hormone therapy can increase their length by nearly an inch (one cm) according to the first clinical study comparing outcomes for such men others.

The findings from the Phase 1 trial could have broad implications says the studys lead author Michael Stokes Professor of Human Reproduction and Public Health at the University of Bristol in Bristol U. K. This study is a direct confirmation that the application of obesity- and gender-specific reparative therapy can extend a persons lives he says.

Transgender men are typically happiest being taken care of exclusively as male says the studys lead author Aiman Naser Khan a partner in the INSIGHT study group at the University of Bristol. Hormone therapies can modify hormone function giving them the ability to have normal sexual functioning he says. In the study which was published in Global Diabetes Research and Education the trial involved 46 transgender men (23 men years of age) who were transitioned after taking hormone therapy (HT) for the first time.

Their partners in the trial (23 men) were matched for sex ethnicity and weight. All participants were assessed for mental status and physical activity. Mental status is the mental state of being physically present in oneself and in the world due to an alteration in consciousness vision memory and mood. Physical activity levels are a persons ability to actively move think and feel says the studys senior author Dr. Kyle Bohannon of the University of Bristol.

The full length increases the average length of the participants average body length by an incremental 5. 7 cm (almost 13 inches) between the 2 weeks after therapy ended and 2 years after transition. Similar lengths were found among men who were classified as obese borderline overweight or obese (BMI over 25). The main finding was that there was no significant difference in average BMI between the 2 groups (BMI over 25). Average-BMI weight cuts were similar regardless of whether the men lost weight or not though BMD was significantly affected by fat mass i. e. a greater reductions were seen with fat mass only.

The same 3D body scan was used to assess patients general health. MRI brain scans were done at the end of the study to ensure typical brain features of men and women were not going awry.