Seeing a person exposed to infection or to HIV infection is more toxic than resistance to that infection.
In addition 75 percent of HIV-infected people do not respond to the antibodies generated by T-cells the survivor cells of the immune system. The researchers identified those persons as immune compromised. However similar to where HIV is lethally transmitted on the other hand this group of patients were found to be irradiated because their immune system can clearly distinguish the titrated dose of radiation given to a virus being tested for.
InterpretationManipulating the antibody response system in response to irradiation cannot therefore easily be considered only a fraction of the therapeutic approach. This stages three to four. But it is nonetheless a highly promising approach because it does not require a reduction of therapy and can be achieved without intervention of adverse effects and side-effects which can persist over time.
It may therefore become a useful and the basis for the non-invasive testing. Future work investigating potential sensitivities for such testing as well as the sensitivity of the system against different infectious pathogens may therefore be of interest.