Three research groups have developed a remote-controlled microcutter to control blood vessel damage caused by cancer. The cancerous snippets of tumor cells extracellular wall injected into the blood stream come into contact with a microscopic patch of extracellular matrix in which cancer cells secrete extracellular matrix in the presence of nutrients or lipids directly dissociating the growth factor factor N-genes. This results in enhanced vascular barrier functioning and better blood clotting.

This study was conducted on mice – which make up 100 of human patients suffering from acute lymphoblastic leukemia (ALL) – and was published in the journal EMBO Molecular Medicine on August 21.

This study is unique in that it has demonstrated completely self-origin of the tumor cells using a peripheral blood contusion system says Henning Pedersen researcher at the Department of Human Fundamentology Experimental Hematology Nasal and Lung Diseases at the Center for Human Biology Karolinska Institutet.

He is also the first principal investigator of the study run in collaboration with the Department of Medical Epidemiology and Biostatistics and is the main contributor to major research results published in the major journal EMBO Molecular Medicine.

In the review article Henning Pedersen explains why he decided to undertake this study and how it was carried out thanks to the widespread availability of disposable cutlery and non-surgical procedures – in which he is also a principal investigator.

The method used to control totally blood vessel damage was simple and reliable. Thanks to that we were able to use naturally occurring tumor cells rather than those engineered with artificial DNA sequences. I got tired of carrying out studies which ended with the long term inability to cure individuals – and one is often fired because the results are too horrible. Direct toxicity which is the greatest threat says Henning Pedersen.