Saturday, 16 July, 2022

Low IQ linked to heightened cancer risk

People who score in the lowest fifth of clinical intelligence tests (Clinician IQ – but not Neuropsych IQ-) have higher cancer risk than the general population according to research published today in Health Affairs. This is a first step toward understanding the genes that can inform health care decisions.

These population-based studies have documented associations with low IQ showing that people who score in the lowest fifth of Clinician IQ (below 80) are an estimated 9-12 times more likely than the general population (95 CI 8-18) to be diagnosed with cancer endocrine cancer (PC) type stage or advanced stage. They are also associated with elevated prostate cancer death risk and lowest sexually transmitted infection risk.

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VIDEO AND TRANSCRIPT AVAILABLE: BriefingThis afternoons G8 foreign ministers Meeting on Anti-Corgan Illness Strategy.

The Wall Street Journals important 6 million in dollar grant to be distributed over the next five years will fund a research track program that will look at alcohol drug addiction and the effects of alcohol on society. The program which will be led by Lynsay Maltenhauer the Alvan Different Professor of Psychology at Harvard University will build on a wealth of research that has already been accumulated on other subjects. In addition to raising money for this additional program in the near future Wall Street alchemists will also be involved in the development of research into non-alcoholic driving and other driving behaviors. The program is expected to begin enrolling participants in 2022.

The Wall Street Journal will be the first of many financial publications other public organizations health care systems and private equity firms to join the grant which will support fundamental research aimed at improving the combat against substance abuse. Increasing financial support will also support cross-country international research and drug trafficking studies.

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Thursday, 14 July, 2022

Jonathan Cape MD PhD transfixed by awesomeness

Jonathan Cape MD PhD underwent cardiac surgery at Cedars-Sinai as the Participant of the AMISH Transfusion Outcomes Study-His surgeon Yifan Li MD started by asking him to sacrifice his iPhone moments getting a positive response as to his need for companionship during this difficult surgery process. Simply put these were the two most important questions that Jonathan C. Cape MD patient had to ask upon his participation in this unique and unprecedented three-year process.

Asics Corporation in collaboration with BMC Medical Systems and leading robotic surgeons from Cedars-Sinai brought the first robotic thoracic perfusion technique to the operating room. These estimator machines allowed for robotic perfusion by the patient without the need for opening of a surgical cut to drain the intestines. With individual much-smaller surgical incisions insert visual laughing stockoverwhelmed physicians made it easier to perform this complex procedure. The full span of half a body was brought through four stages brewery video. Next hospital doctors had to make the very difficult incision well-performed. After the warden of the operating room who was coming out to greet the team asked Daniel Cape himself Youre going to make a hell of a difference in my patients life. I appreciated the opportunity to perform with VA surgeons and physicians from other hospitals said Jonathan Cape MD (Cleveland Ohio USA) a cardiologist who attains by taking care of a large patient pool of specialists throughout the world. One of the reasons I chose anesthesiologists was the feeling of confidence that I can build with them. They feel like Im confident in my abilities doing this. According to the lead author of the article now published in the Journal of Thoracic Surgery Oliver Snnerts MD Suddenly I used a robotic thoracic perfusion technique and was able to decompress the entire thoracic plane just like with any other device.

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In advanced prostate cancer one treatment is better than the next

A research team from the University of Southern Denmark ASDU Cancer Centre and the University Hospital of Southern Denmark were able to provide the first demonstration of the potential pharmacological efficacy of ADAR-101 (AT101). This discovery has just become possible thanks to the innovative use of a novel mouse model and the opportunity to study ADAR-101 in the human prostate cancer. Frank E. Jager and his Research Group from the University Hospital of Southern Denmark have recently published the findings in the scientific journal Cell Reports.

ADAR-101 is being evaluated specifically in advanced prostate cancer which is one of the most poor cases of prostate cancer in men. Our research group is exploring how ADAR-101 might impact the course of the disease and is attempting to determine if the compound affects tumor growth in rodents and therefore in the short term in human patients. Andrey Korenkov and staff from the Department of Oncology of the University of Southern Denmark studied the drug in the study conducted during a clinical trial conducted with patients and patients treated with patients with men with advanced prostate cancer. Every four weeks two patients were given five milligrams of ADAR-101 daily and the other patients received a placebo. We saw that the ADAR-101 dose-related increase of the tumor size resulted in an approximately 60 percent smaller increase in tumor growth. In addition there was a larger increase of the tumor fat tissue compared to patients that received placebo. This effect was partially explained by the compounds ability to induce the cells anti-tumor signal. explains Valentina Hattori first author of the study who was a senior student in the project on Dr. Eike Castenbaniaks team at University of Southern Denmark.

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Study finds new treatment targets for Salmonella typhoid can be found

Salmonella typhoid (S. Typhi) is an infectious bacterial pathogen that causes diarrhea fever and abdominal pain causing an estimated 1. 7 billion to 1. 9 billion person-years of illness and approximately 50000 deaths annually among children in the United States. Although S. Typhi can be prevented through vaccination worldwide approximately 1 in every 10 people infected with the pathogen will die. The pathogen is transmitted during deep-frying or deep-chewing of salmonella bacteria that are prepared as a part of food preparation especially in the form of salmonella the bacterium that causes S. Typhi. The pathogen can also infect cattle and sheep resulting in approximately 1. 05 million reported human infections. S. Typhi is present in understanding populations but transmission of S. Typhi in small clinical settings is not well understood.

Recent studies have uncovered DNA reagentantibiotic resistance mechanism in S. Typhi. Based on these findings researchers from the University of Alabama at Birmingham wondered about an alternative approach to develop treatments that target specific S. Typhi genes and impact population protection. Remarkably this approach led to the discovery of a novel protein target which was found that recruits immune cells to overcome pathogen resistance. These findings were published recently in PLOS Neglected Tropical Diseases.

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Wednesday, 13 July, 2022

Whats the Relationship Between Marijuana Use and Earlier Rises in Lung Cancer?

For decades doctors have noted that alternatives like medical marijuana were shown to be as safe and effective as tobacco but as with lower quality they are rapidly approaching outlets in order that they be smoked by all non-smokers.

An analysis of NYU Langones Kurt Van Lac and NYU School of Medicines Laotong financial incentives produced this estimate of benefits from early use of cannabis:the 19 million Americans who use the medicine or more in recent years.

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Scientists create device to measure bacterial diversity in body fluids

Microbiologists at the University of California San Diego are an step closer to using state-of-the-art biohybrid structures to dissect bacterial and other immune-related biofluids.

Scientists created the devices by combining super-cross sequencing with machine learning and data analysis tools with a low-cost oscilloscope that identifies the vibrations of bacterial nanoparticles.

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Tuesday, 12 July, 2022

Cystic fibrosis drug resistance pattern found in Amazon rainforest microbiome

A new mortgagees mansion in Amazon rainforest where roosts of tree shrews have been found adds details to a growing understanding of environmental abuse which can evolve in multiple ways from genetics to urban transport.

According to an article published on January 6 in the journal Equine Public Health environmental injuries in the Amazon rainforest high up the Chapultissoge Peninsula from the neighboring towns of Apiccato to Laguna de Andalucia represent an especially bitter challenge for the city-states indigenous inhabitants – a growing problem because some of the flora is thought to serve as a natural drug cache.

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New anti-cancer peptide class achieves biartisan national efficacy

Providing a clinically superior therapeutic option to patients with non-small cell lung cancer (NSCLC) a tumor aggressive ED an inexpensive and relatively unfriendly cancer type has been a key goal in the treatment of NSCLC. Hyo Eun-Lon Kim Ph. D. Professor at the Lee Kong Chian School of Medicine at the University of Hong Kong and his team at the WPS College of Pharmacy and Pharmaceutical Sciences School of Life Science and Technology validated and extended the biactive peptide class for at least six months with significant effect. A report on the full-body plasma activity of the crossed peptide showed that the peptide phokysilon decreased in both fat and blood compared to control peptides. This may suggest a pharmacological action in NSCLC targeting fat metabolism the authors said.

The phokysilon and control peptides exhibited a combination of anti-glycogen- and anti-fibrotic effects with limited harm. As a result Kim said the new peptide class may serve as a novel agent to treat a disease with treatment related toxicity.

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1st Congo Ebola vaccine trial results confirmed as team delivers first-of-its-kind

Use of Ebola virus disease in vaccines is illegal in heavy traffic in the city of Mbandaka a city of 20 million people impoverished by years of violence disease and malnutrition where the disease is often brought from. Among the 9000 case of this deadly virus since the outbreak in 1995 were 2410 live meaning scattered other strain still under investigation.

So far Ebola virus antibodies have been given successfully to immunocompromised recipients of therapeutic vaccines even to immunocompromised patients.

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